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Below are the publications this lab has been associated with. Click the links to open the publications in a new window.
| Regulation of myeloid leukaemia by the cell-fate determinant Musashi
Ito T, Kwon Y, Zimdahl B, Congdon K, Blum J, Lento W, Zhao C, Lagoo A, Gerrard G, Foroni L, Goldman J, Goh H, Kim S, Kim D, Chuah C, Oehler V, Radich J, Jordan C, & Reya T. 2010.
Nature Advanced Online Publication | | 
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| Itraconazole, a Commonly Used Antifungal that Inhibits Hedgehog Pathway Activity and Cancer Growth
Kim J, Tang J, Gong R, Kim J, Lee J, Clemons K, Chong C, Chang K, Fereshteh M, Gardner D, Reya T, Liu J, Epstein E, Stevens D, & Beachy P. 2010.
Cancer Cell 17(4):388-99 | |
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| Pleiotrophin regulates the expansion and regeneration of hematopoietic stem cells
Himburg H, Muramoto G, Daher P, Meadows S, Russell J, Doan P, Chi J, Salter A, Lento W, Reya T, Chao N, & Chute J. 2010.
Nature Medicine 16:475-82 | |
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| Hedgehog signalling is essential for maintenance of
cancer stem cells in myeloid leukaemia
Zhao C*, Chen A*, Jamieson CH, Fereshteh M, Abrahamsson A, Blum J,
Kwon HY, Kim J, Chute JP, Rizzieri D, Munchhof M, VanArsdale T, Beachy PA & Reya T. 2009.
Nature Advance Online Publication Jan 25th | |
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|  | | Research Highlights | | | | Killing Hedgehog to treat CML
Chenette E (2009) Nature Reviews Cancer | |
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| | | Research Highlights | | | | Self-renewing blood and leukemia cells need hedgehog
Alves S (2009) Nature Reports Stem Cells | |
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| | Divide and Conquer: How asymmetric division shapes cell fate in the hematopoietic system
Congdon KL and Reya T. 2008.
Current Opinion In Immunology 20:302-7 | |
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| Activation of Wnt signaling in hematopoietic regeneration
Congdon KL*, Voermans C*, Ferguson EC, DiMascio LN, Uqoezwa M, Zhao C and Reya T. 2008.
Stem Cells 26:1202-10 | |
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| Loss of beta-catenin impairs the renewal of normal and CML stem cells in vivo.
Zhao C, Blum J, Chen A, Young HK, Jung SH, Cook MP, Lagoo A, and Reya T. 2007.
Cancer Cell. 12:528-541. | |
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| | | Previews | | | | Knocking the Wnt out of the Sails of Leukemia Stem Cell Development.
Deshpande AJ and Buske C (2007) Cell Stem Cell, 1:597-598. | |
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| | Imaging hematopoietic precursor division in real-time.
Wu MF, Kwon HY, Rattis FM, Blum J, Zhao C, Ashkenazi R, Jackson TL, Gaiano N, Oliver T and Reya T. 2007.
Cell Stem Cell, 1:541-554. | |
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| | | Previews | | | | Asymmetric cell division in normal and malignant hematopoietic precursor cells.
Schroeder T (2007) Cell Stem Cell, 1:479-481. | |
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| | Identification of Adiponectin As a Novel Hematopoietic Stem Cell Growth Factor.
DiMascio LN, Voermans C, Uqoezwa M, Duncan AW, Lu D, Wu J, Sankar U, and Reya T. 2007.
Journal of Immunology. 178(6):3511-3520. | |
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| Wnt signalling in stem cells and cancer.
Reya T and Clevers H. 2005
Nature. 434(7035):843-50. | |
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| Integration of Notch and Wnt signaling in hematopoietic stem cell maintenance.
Duncan AW*, Rattis FM*, Dimascio LN, Congdon KL, Pazianos G, Zhao C, Yoon K, Cook JM, Willert K, Gaiano N, and Reya T. 2005
Nature Immunology. 6(3):314-22. | |
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| | | News and Views | | | | Defining 'stemness': Notch and Wnt join forces?
Jacobsen SE. (2005) Nature Immunology, 6(3):234-6. | |
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| | | Research Highlights | | | | Notch balances self-renewal and differentiation.
Honey K. (2005) Nature Reviews Immunology, 5:184-185. | |
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| | Wnt signaling in the stem cell niche.
Rattis FM, Voermans C, and Reya T. 2004.
Current Opinion in Hematology. 11(2):88-94. | |
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| The elements of stem cell self-renewal: a genetic perspective.
Pazianos G, Uqoezwa M, and Reya T. 2003
Biotechniques, 35(6):1240-7. | |
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| Wnt proteins are lipid-modified and can act as stem cell growth factors.
Willert K, Brown JD, Danenberg E, Duncan AW, Weissman IL, Reya T, Yates JR 3rd, and Nusse R. 2003
Nature. 423(6938):448-52. | |
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| A role for Wnt signalling in self-renewal of haematopoietic stem cells.
Reya T*, Duncan AW*, Ailles L, Domen J, Scherer DC, Willert K, Hintz L, Nusse R, and Weissman IL. 2003
Nature. 423(6938):409-14. | |
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| | | News | | | | Purified signaling protein stimulates stem cell proliferation.
Couzin J. (2003) Science, 300(5620):722. | |
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| | | News and Views | | | | Manipulating hematopoietic stem cell amplification with Wnt.
Eaves CJ. (2003) Nature Immunology, 4(6):511-2. | |
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| | Regulation of hematopoietic stem cell self-renewal.
Reya T. 2003
Recent Progress in Hormone Research, 58:283-95. | |
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| Stem cells, cancer, and cancer stem cells.
Reya T*, Morrison SJ*, Clarke MF, and Weissman IL. 2001
Nature, 414(6859):105-11. | |
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| Wnt signaling regulates B lymphocyte proliferation through a LEF-1 dependent mechanism.
Reya T, O'Riordan M, Okamura R, Devaney E, Willert K, Nusse R, and Grosschedl R. 2001
Immunity, 13(1):15-24. | |
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